Laminin is the major glycoprotein component of basement membranes, and has a molecular weight of 850,000 daltons. This preparation of mouse Laminin was isolated from the Engelbreth-Holm-Swarm (EHS) sarcoma and is supplied at a concentration of 0.5-2.0 mg⁄ml.
Key functions include:
• Modulation of cell attachment, cell spreading, cell growth and motility
• Binding to itself and other matrix compounds
• Promotion of epithelial differentiation
• Modification of leukocyte function
• Stimulation of neurite outgrowth
Supplied: 1 mg in 50 mM Tris-HCL (pH 7.4), 0.15 M NaCl
Performance qualification (cell attachment): Half-maximal cell attachment of MG63 cells at 37°C: ≤ 20 ug⁄ml
