V-9302

英文名：V-9302

CAS号：1855871-76-9

分子式：C₃₄H₃₈N₂O₄

分子量：538.6765

保存温度：-10 to -25°C

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中文名称	V-9302
英文名称	V-9302
英文别名	(S)-2-amino-4-(bis(2-((3-methylbenzyl)oxy)benzyl)amino)butanoic acid;s8818;ZB1562;BDBM50140122;(2S)-2-Amino-4-[bis[[2-[(3-methylphenyl)methoxy]phenyl]methyl]amino]butanoic acid;V-9302;HY-112683;G60987;CS-0062616;CHEMBL3754053;V-9302?;AKOS040758738;SCHEMBL26092192;AS-84793;(S)-2-Amino-4-(bis(2-((3- methylbenzyl)oxy)benzyl)amino)butanoic acid;AC-35594;(2S)-2-amino-4-[bis({2-[(3-methylphenyl)methoxy]phenyl}methyl)amino]butanoic acid;EX-A2965;1855871-76-9;(2S)-2-amino-4-[bis[[2-[(3-methylphenyl)methoxy]phenyl]methyl]amino]-butanoic acid
CAS No.	1855871-76-9
分子式	C₃₄H₃₈N₂O₄
分子量	538.68

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说明

Biochem/physiol Actions

Competitive antagonist of the amino acid transporter ASCT2 (SLC1A5) with anti-tumor activity

V-9302 is a selective competitive antagonist of the amino acid transporter ASCT2 (SLC1A5) with anti-tumor activity. V-9302 caused reduced cellular viability and increased cell death in a panel of cancer cell lines and reduced tumor cell growth in both HCT-116 and HT29 (Fig. 5f) xenograft models.