产品名称Recombinant CD38 Antibody
别名分化簇38 | ADP-核糖基环化酶 | CD38单克隆抗体 | 小鼠抗人CD38抗体
英文别名Acute lymphoblastic leukemia cells antigen CD38 antibody | ADP ribosyl cyclase 1 antibody | ADP ribosyl cyclase antibody | ADP ribosyl cyclase/cyclic ADP-ribose hydrolase antibody | ADP-ribosyl cyclase 1 antibody | ADPRC 1 antibody | ADPRC1 antibody | cAD
规格或纯度无动物源, 无载体, 重组, ExactAb™, 无叠氮钠, 已验证, 高性能, ≥95%(SDS-PAGE), 见COA
生化机理Synthesizes cyclic ADP-ribose (cADPR), a second messenger for glucose-induced insulin secretion. Synthesizes the Ca2+ mobilizer nicotinate-adenine dinucleotide phosphate, NAADP+, from 2'-phospho-cADPR and nicotinic acid, as well as from NADP+ and nicotinic acid. At both pH 5.0 and pH 7.4 preferentially transforms 2'-phospho-cADPR into NAADP+, while preferentially cleaving NADP+ to cADPR and ADPRP rather than into NADDP+. Has cADPR hydrolase activity.
宿主种属小鼠(Mouse)
特异性Human CD38
种属反应性人(Human)
免疫原Fetal human thymocytes.
阳性对照Flow Cytometry: Human peripheral blood monocytes
偶联Unconjugated
